The 2021 Maritime Regulations for Transiting the Panama Canal contains the most recent Notices to Shipping, Amendments and Regulations for the safe transfer of cargo through the Panama Canal (by ship).
 
Vessel Requirements
Harbor Operations
Communications on Transit Activities
Illegal Activities on Transiting Vessels
Official, Courtesy and Guest Transits
Embarking or Disembarking During Transit
Panama Canal Transit Reservation System
Attachment of Vessels by Panama Maritime Tribunals
Marine Accident Investigations
Operational Equipment Tests
Operation of Commercial and Non Commercial Small Craft in Panama Canal Waters
Panama Canal Shipboard Oil Pollution Emergency Plan (PCSOPEP) Requirements
Implementation of ISPS Code Requirements of the Panama Canal